An economical Nanopore sequencing assay for human papillomavirus (HPV) genotyping
نویسندگان
چکیده
منابع مشابه
Comparison of DNA sequencing and Roche Linear array in human papillomavirus (HPV) genotyping.
BACKGROUND Human papillomavirus (HPV) is the etiological agent of cervical cancer. HPV genotyping is important to determine the presence of high-risk types. Recently, a new HPV genotyping method, the Roche Linear array genotyping test, was introduced and is compared here with a sequencing-based HPV genotyping system. MATERIALS AND METHODS A series of 102 women (age range 30-55 years) shown to...
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Persistent infection with high-risk types of human papillomavirus (HPV) is a necessary step in the development of cervical cancer. The incorporation of HPV detection into cervical screening programs may improve the ability to identify women at risk of cervical cancer. We recently evaluated the performance characteristics of a newly developed HPV detection assay, the GenoArray (GA) genotyping as...
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We evaluated a commercialized PCR assay, Linear Array, that detects 37 human papillomavirus (HPV) genotypes, using a sample of liquid cytology specimens (n = 534). We found a strong association of an increasing level of HPV risk (HPV type 16 [HPV16] > HPV18 > other carcinogenic types > noncarcinogenic types > negative specimens) with increasing severities of cytologic interpretations (P(Trend) ...
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ژورنال
عنوان ژورنال: Diagnostic Pathology
سال: 2020
ISSN: 1746-1596
DOI: 10.1186/s13000-020-00964-6